Neuro Plus Review 2026: Every Ingredient, Honestly Assessed

By Daniel Hayes · Updated July 31, 2026· 10 min read

Last updated: 27 July 2026 · This is our own product. We have reviewed it the way we would review anyone else's, including the parts we would change.

Before anything else: there are several unrelated products called Neuro Plus. If you searched for Neuro PS Gold Plus, NeuroClear Gold Plus, a Neuro Plus syrup, or a Neuro Plus sold by another brand, this is not that product. This review covers Peremis Neuro Plus Brain and Focus Formula, a 60 capsule bottle sold at peremis.com.

Short verdict: Neuro Plus is a broad brain and focus formula that combines a near complete vitamin and mineral profile with a 609 mg nootropic blend containing bacopa, phosphatidylserine, DMAE, huperzine A and DHA. The vitamin side is genuinely well dosed. The botanical side is a proprietary blend, which means individual amounts are not disclosed, and with 17 ingredients sharing 609 mg most of them cannot be at a studied dose. It suits someone who wants one broad daily capsule. It does not suit someone who wants a clinical dose of any single nootropic.

Below is every ingredient, what it is there for, and how the amount compares to research where research exists.

The vitamins and minerals

This part of the formula is straightforward and honestly quite good. Per two capsule serving:

Nutrient	Amount	Percent DV	Comment
Vitamin B6	12 mg	706%	Well within the safe upper limit
Pantothenic acid	12 mg	240%
Folate	680 mcg DFE	170%	As folic acid rather than methylfolate
Vitamin D	25 mcg	125%	1,000 IU, a sensible daily amount
Vitamin C	125 mg	139%
Vitamin E	40 mg	266%	Synthetic DL form, less well absorbed than natural D form
Thiamin, riboflavin, niacin	1.4 / 1.7 / 12.5 mg	117 / 131 / 78%	Solid B complex coverage
Zinc	10 mg	91%	As oxide, the least absorbable form
Magnesium	50 mg	12%	As oxide, poorly absorbed. See our magnesium guide
Selenium	50 mcg	91%	Amino acid chelate, a good form
Iron	2.6 mg	14%	Small amount, but see the warning below
Choline	50 mg	9%	Modest. Choline research typically uses far more

Honest read. If you are not already taking a multivitamin, this covers most of the ground well. Two things we would change. The magnesium and zinc are both oxide forms, which are the cheapest and least absorbable options, and our own magnesium guide says exactly that. And the folate is folic acid rather than methylfolate, which matters to a minority of people who convert folic acid less efficiently.

The nootropic blend, ingredient by ingredient

The label lists a Proprietary Blend of 609 mg containing 17 ingredients. Under US labelling rules, proprietary blends must list ingredients in descending order by weight but do not have to disclose individual amounts.

That means the order below tells you something. DMAE is first, so it is the largest component. Huperzine A is last, so it is the smallest. But the actual milligrams are not published, including to us writing this. Here is what each one is doing there.

The ones with real research behind them

Bacopa monnieri. The best supported botanical in this formula. Human trials on memory typically use around 300 mg a day of a standardised extract, taken for eight to twelve weeks, because bacopa builds slowly rather than acting acutely. It sits sixth in the blend order here, so it is very unlikely to be at 300 mg.

Phosphatidylserine. A phospholipid found in cell membranes with a reasonable research record for age related memory complaints. Trials generally use 100 to 300 mg a day. It sits second from last in the blend order.

DHA. An omega 3 fatty acid genuinely important for brain structure. Trial doses run into the hundreds of milligrams to grams. In a 609 mg blend of 17 ingredients, the amount here will be small. This is also where the fish allergen comes from.

Green tea extract. Third in the blend. Contains L theanine and catechins, and is a reasonable inclusion for calm focus.

The one that is pharmacologically active

Huperzine A. This deserves its own paragraph, because it is not a gentle botanical. Huperzine A is a reversible acetylcholinesterase inhibitor, meaning it slows the breakdown of acetylcholine, a neurotransmitter involved in memory. That is the same mechanism used by some prescription medicines.

Typical supplement amounts are measured in micrograms rather than milligrams. Practical implications worth knowing:

• It can add to the effects of cholinergic medications, and oppose anticholinergic ones. If you take any prescription medication, mention this formula to your pharmacist.
• Long term continuous use has limited safety data, which is why many people using huperzine A take periodic breaks.
• Cholinergic side effects such as nausea, vivid dreams or muscle twitching can occur.

The one we are least convinced by

DMAE. Listed first, so it is the largest single component of the blend by weight. DMAE has been used in nootropic formulas for decades, and the human evidence for cognitive benefit in healthy adults is weak. It has also faced regulatory scrutiny in some markets. It is not the ingredient we would put the most weight behind, and it is the one we would most want to see replaced with more bacopa or phosphatidylserine.

The supporting cast

L glutamine, glutamic acid, inositol, GABA, bilberry, grape seed, grapefruit seed, olive leaf, cassia bark, licorice root, boron and vanadium make up the rest. Several are reasonable antioxidants. GABA is worth a note: taken orally it does not readily cross into the brain, so its inclusion is more traditional than mechanistic. Licorice root is worth knowing about if you have high blood pressure, though at blend level amounts the exposure is very small.

The honest problem with a 17 ingredient blend

We criticise proprietary blends elsewhere on this blog, so it would be dishonest not to apply the same standard here.

609 mg divided across 17 ingredients averages about 36 mg each. Bacopa research uses 300 mg. Phosphatidylserine research uses 100 to 300 mg. Even allowing for descending order, meaning the first few ingredients get considerably more than 36 mg, the arithmetic does not leave room for several ingredients to be at a studied dose simultaneously.

That is not unique to this product. It describes most multi ingredient nootropics on the market. But it is the honest way to set your expectations: this is a broad daily foundation, not a clinical dose of bacopa in a capsule.

If a fully disclosed label matters more to you than breadth, that is a legitimate reason to choose something else, and we would rather tell you that than have you find out in a month.

Allergens and warnings you need to read

Contains soy and fish (tuna). The phosphatidylserine is soy derived and the DHA is from fish. Do not take this if you have a fish or soy allergy.

Contains iron. Accidental overdose of iron containing products is a leading cause of fatal poisoning in children under six. Keep this product out of reach of children.

Speak to your pharmacist before taking this alongside any prescription medication, because of the huperzine A.

Not suitable during pregnancy or breastfeeding, or under 18.

How to take it

Two vegetable capsules once a day, 20 to 30 minutes before a meal, with a full glass of water.

A note on timing. Some people find nootropic formulas containing huperzine A produce vivid dreams if taken late in the day. Morning dosing avoids that. Bacopa in particular is also gentler on the stomach with food, so if you get any queasiness, take it with breakfast rather than before it.

Give it eight weeks. Bacopa and phosphatidylserine both build gradually, and nothing in this formula is designed to be felt within an hour. If you are expecting a stimulant effect, this is not that. There is no caffeine in it.

Who this suits, and who it does not

It suits you if you want one broad daily capsule covering vitamins, minerals and a range of brain focused botanicals, you are not already taking a multivitamin, and you value convenience over maximum dose of any single ingredient.

It does not suit you if you have a soy or fish allergy, you take prescription medication and would rather avoid a cholinesterase inhibitor, you want a fully disclosed label with every amount printed, or you specifically want bacopa at the dose used in research. In that last case a single ingredient standardised bacopa product is the right tool.

Frequently asked questions

What is in Neuro Plus?

Neuro Plus contains a full vitamin and mineral profile plus a 609 mg proprietary blend of 17 ingredients including DMAE, L glutamine, green tea extract, bacopa monnieri, inositol, bilberry, GABA, grape seed, phosphatidylserine and huperzine A. The serving is two vegetable capsules once a day. It contains soy and fish.

Does Neuro Plus contain lion's mane?

No. Neuro Plus contains bacopa monnieri, phosphatidylserine, DMAE and huperzine A, but no lion's mane or any mushroom. If lion's mane is what you are after, that is a separate product and a separate ingredient category.

How much bacopa is in Neuro Plus?

The exact amount is not disclosed, because bacopa sits inside a proprietary blend. Blend ingredients are listed in descending order by weight, and bacopa is sixth of 17 in a 609 mg blend, so it is very unlikely to reach the 300 mg used in memory research.

How long does Neuro Plus take to work?

Give it eight weeks. Bacopa and phosphatidylserine, the two best supported ingredients, both build gradually over weeks rather than acting acutely. There is no caffeine in the formula, so you should not expect a same day stimulant effect.

Is Neuro Plus safe to take with medication?

Speak to your pharmacist first. Neuro Plus contains huperzine A, a reversible acetylcholinesterase inhibitor with genuine pharmacological activity, which can interact with cholinergic and anticholinergic medications. It also contains iron, which some people should not supplement.

Does Neuro Plus contain caffeine?

No. It contains green tea extract, which can contain small amounts of caffeine depending on the extract, but the formula is not built as a stimulant. It is designed as a daily foundation rather than an acute energy product.

Can I take Neuro Plus with a multivitamin?

Usually there is no need. Neuro Plus already contains a near complete vitamin and mineral profile, several at over 100 percent of the daily value. Taking both means doubling up, which is unnecessary for most nutrients and worth avoiding for iron in particular.

Is Neuro Plus worth it?

It depends what you want. As one capsule covering vitamins, minerals and a broad range of brain focused botanicals, it is a reasonable daily foundation. As a way to get a research level dose of any single nootropic, it is not, because 17 ingredients sharing 609 mg cannot all be at a studied amount.

The bottom line

Neuro Plus does what a broad spectrum brain formula is meant to do. The vitamin and mineral side is genuinely well constructed, the botanical side includes several ingredients with real research behind them, and two capsules a day is easy to stick with.

What it is not is a high dose single ingredient product. The proprietary blend means you cannot verify what you are getting of anything, and the arithmetic says most of those 17 ingredients are present in modest amounts.

We would rather write that ourselves than have you work it out later. If breadth and convenience are what you want, this delivers. If you want to hit the bacopa dose from the studies, buy bacopa.

See the full panel and current price on the Neuro Plus Brain and Focus Formula page. Comparing your options first? Read our brain and focus supplement guide, or learn the general skill in how to read a supplement label.

About this review. Written by the Peremis Editorial Team about our own product. We have applied the same standards we apply to other brands elsewhere on this blog, including criticising the proprietary blend, naming the cheaper mineral forms, and telling you which ingredient we are least convinced by. Every figure comes from the current Supplement Facts panel. We make no medical claims and a supplement is not a substitute for medical care.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult a licensed healthcare provider before starting a new supplement, especially if you are pregnant, nursing, taking medication, or have a medical condition.